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Jurnale medicale
6 Februarie 2015 22:00
This study compared the reciprocal control of agonist and antagonist muscles in individuals with and without spinocerebellar ataxia (SCA) and evaluated the effect of a 4-week leg cycling regimen on functional coordination and reciprocal control of agonist and antagonist muscles in patients with SCA. mai mult
Archives of Physical Medicine and Rehabilitation
6 Februarie 2015 22:00
Cancer stem cells (CSCs) are a subpopulation within a tumor, which possesses the characteristics of self-renewal, differentiation, tumorigenicity, and drug resistance. The aim of this study was to target the colorectal CSC marker CD133 with an131I-labeled specific monoclonal antibody (AC133 mAb) in mai mult
Nuclear Medicine and Biology
6 Februarie 2015 22:00
The myeloperoxidase inhibitor AZD3241, has been selected as a candidate drug currently being developed to delay progression in patients with neurodegenerative brain disorders. Part of the decision tree for translation of AZD3241 into clinical studies included the need for assessment of brain exposur mai mult
Nuclear Medicine and Biology
6 Februarie 2015 11:54
Objective

The effects of vitamin D in the elderly are inconsistent. The aim of this study was to evaluate the association between vitamin D status and the metabolic syndrome (MetS) in the elderly, as well as between vitamin D status and the components of MetS (i.e. serum glucose, triglycerides (TG),

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Background

Reports conflict concerning measurements of plasma metanephrines (MNs) for diagnosis of pheochromocytomas/paragangliomas (PPGLs) by immunoassays compared with other methods. We aimed to compare the performance of a commercially available enzyme-linked immunoassay (EIA) kit with liquid chr

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Objective

Management of insulinomas in the context of MEN1 remains poorly studied. The aim of this study was to evaluate long-term results of various surgical approaches in a large cohort of insulinoma–MEN1 patients.

Design and methods

Consecutive insulinoma–MEN1 patients operated on for a nonmetas

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Context and objective

Patients with cranial diabetes insipidus (CDI) are at risk of developing both hypernatraemia and hyponatraemia, due to the condition itself or secondary to treatment with vasopressin-analogues or during administration of i.v. fluids. We aimed to assess the frequency and impact

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Objective

MicroRNAs (miRNAs) are involved in the regulation of adiposity, but functional studies have yielded inconclusive results. Examining the associations of circulating miRNAs levels with obesity and insulin sensitivity in humans may lead to improved insights.

Design and methods

Serum samples

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Objective

The objective was to assess the amount of vitamin D3 stored in adipose tissue after long-term supplementation with high dose vitamin D3.

Design

A cross-sectional study on 29 subjects with impaired glucose tolerance who had participated in a randomized controlled trial with vitamin D3 20 0

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Objective

Mutations in the glucokinase (GCK) gene, along with hepatocyte nuclear factor 1A (HNF1A) gene mutations, are the most frequent cause of maturity-onset diabetes of the young (MODY). GCK-MODY patients are typically characterized by a moderate fasting hyperglycemia; however, little is known ab

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Objective

To assess whether single nucleotide polymorphisms of HSD17B5 (AKR1C3) (rs1937845 and rs12529) and HSD17B6 (rs898611) are associated with polycystic ovary syndrome (PCOS) in a Chinese population.

Design

A case–control study was conducted to investigate the relation between HSD17B5 and HSD1

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Objective

Germany was iodine deficient until the mid-1990s when a nationwide iodine fortification program became effective. It is expected that after a longer period of sufficient iodine supply, median TSH values in the general population will shift to the right. Hence, the previous TSH reference ra

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54

Mineralocorticoid receptor antagonists have been used in patients with aldosterone-producing adenomas (APAs) as a test designed to predict the blood pressure (BP) outcome of surgery. They are commonly used in patients undergoing adrenalectomy to reduce BP and increase plasma potassium levels during

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Objective

There are scarce reports regarding the prognosis of a second course of antithyroid drug (ATD) therapy on recurrent Graves' disease (GD). The aim of this study was to assess the long-term remission rate after a second ATD therapy and verify significant clinical predictors of a remission.

D mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54

Adrenal crisis is a life-threatening emergency contributing to the excess mortality of patients with adrenal insufficiency. Studies in patients on chronic replacement therapy for adrenal insufficiency have revealed an incidence of 5–10 adrenal crises/100 patient years and suggested a mortality rate

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Objective

To obtain structured information on the diagnostic delay in patients with Cushing's disease (CD) from the patients perspective to provide leverage points for earlier diagnosis.

Design

The study includes 176 patients with ACTH-dependent CD who had received pituitary surgery completed a sel

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Objective

Diabetes mellitus (DM) is associated with endothelial dysfunction, reducing nitric oxide-dependent vasodilation, and increasing production of pro-inflammatory factors, leading to an increased risk of long-term cardiovascular disease. As the effects of phosphodiesterase 5 inhibitors (PDE5i)

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54

Recently, an increased incidence of central diabetes insipidus (CDI) in pregnancy, and less frequently in the post partum period, has been reported, most probably favoured by some conditions occurring in pregnancy. This study was aimed at investigating the influence of pregnancy on a pre-existing po

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Objective

To review the published literature on the effects of telecare intervention in patients with type 2 diabetes and inadequate glycemic control.

Design and methods

A review of randomized controlled trials on telecare intervention in patients with type 2 diabetes, and a search of electronic da

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Objective

Intravenous glucocorticoid (i.v.GC) pulse therapy for Graves' ophthalmopathy (GO) can be associated with acute liver damage (ALD), which was roughly estimated to occur in ~1% of patients, with an overall mortality of 0.4%. The aim of this study was to evaluate the frequency of ALD after th

mai mult
European Journal of Endocrinology current issue
6 Februarie 2015 11:54
Objective

Specific germline mutations in the RET proto-oncogene are correlated with clinical features in multiple endocrine neoplasia type 2A (MEN2A); however, data are scarce regarding differences in clinical profiles dependent on the type of nucleotide and amino acid substitution at the same codon

mai mult
European Journal of Endocrinology current issue
7 Februarie 2015 04:27
The mortality rate among blacks with HIV declined by 28% from 2008 to 2012. In 2013, blacks accounted for 45% of CDC-funded HIV tests and 54.9% of people newly identified as having HIV.
Medscape Medical News mai mult
Medscape Medical News Headlines
6 Februarie 2015 21:05
6 Februarie 2015 21:05
6 Februarie 2015 21:05
Background—

The contemporary practice patterns and role of catheter-directed thrombolysis (CDT) in the treatment of inferior vena cava thrombosis is unknown.

Methods and Results—

The Nationwide Inpatient Sample database was used to identify patients with a principal discharge diagnosis of inferior

mai mult
Circulation: Cardiovascular Interventions current issue
8 Februarie 2015 01:01
Publication date: Available online 7 February 2015
Source:European Journal of Radiology

Author(s): Jens Gempt , Stefanie Bette , Yu-Mi Ryang , Niels Buchmann , Patrick Peschke , Thomas Pyka , Hans-J??rgen Wester , Stefan F??rster , Bernhard Meyer , Florian Ringel

Introduction Histopath mai mult
ScienceDirect Publication: European Journal of Radiology
8 Februarie 2015 01:01
Publication date: Available online 7 February 2015
Source:European Journal of Radiology

Author(s): Mizuki Nishino , Stephanie Cardarella , Suzanne E. Dahlberg , Tetsuro Araki , Christine Lydon , David M. Jackman , Michael S. Rabin , Hiroto Hatabu , Bruce E. Johnson

Objective Interstitia mai mult
ScienceDirect Publication: European Journal of Radiology
6 Februarie 2015 12:00
Background: Individual Cognitive Stimulation Therapy (iCST) is a one to one, carer led psychosocial intervention for people with dementia, adapted from group Cognitive Stimulation Therapy (CST). It is increasingly recognised that involving service users in research is key to developing interventions mai mult
BMC Geriatrics - Latest Articles
6 Februarie 2015 12:00
Background: Escalating numbers of people are experiencing dementia in many countries. With increasing consumer needs, there is anticipated growth in the numbers of people providing diagnostic evaluations, treatments, and care. Ensuring a consistent and contemporary understanding of dementia across a mai mult
BMC Geriatrics - Latest Articles
6 Februarie 2015 22:00
While several publications have reported the treatment of ruptured lung hydatid cysts (HC) in adults, there is limited information on the treatment of children. This study summarizes the treatment approach and outcomes of 11 children with spontaneous rupture of lung HCs into a bronchus. mai mult
Journal of Pediatric Surgery
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